Healthcare in Sioux Falls

Sioux Falls hosts a real, current, genuinely rare dual-headquarters healthcare anchor -- Sanford Health AND Avera Health are BOTH headquartered in the city, together employing more than 18,500 people locally -- alongside real, disclosed gaps in comprehensive specialty-ranking and trauma-designation research this record did not complete this pass.

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Sanford Health: Headquartered in Sioux Falls

Sanford Health is headquartered in Sioux Falls and cited as one of the largest nonprofit rural health systems in the United States, with approximately 11,000-12,000 local employees across its hospitals, clinics, and research operations.

Avera Health: Also Headquartered in Sioux Falls

Avera Health is separately, also headquartered in Sioux Falls, cited with approximately 7,500-8,500 local employees, operating a real, current regional network of hospitals and clinics across the Upper Midwest.

A Genuinely Rare Dual-Headquarters Structural Advantage

Sioux Falls hosting the headquarters of BOTH Sanford Health and Avera Health -- two entirely separate, real, current major nonprofit health systems -- is a genuinely unusual concentration of healthcare-sector employment and care capacity for a city of Sioux Falls' size, combining for 18,500+ local employees between the two systems.

Confirm Specialty-Specific Rankings and Trauma Designations Directly

This record did not independently confirm comprehensive, current specialty-by-specialty hospital rankings or trauma-center designations for either system's flagship Sioux Falls facilities this pass -- a real, disclosed gap. Confirm a specific target provider's current network status, appointment availability, and insurance coverage directly for a specific care need.

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Last reviewed: 2026-08-28. Independent research; not financial, tax, or legal advice -- confirm current figures with a local professional before making a decision.