Healthcare in Peoria

Peoria carries real, substantial regional healthcare access anchored by two major systems -- OSF HealthCare, headquartered directly downtown, and UnityPoint Health -- with healthcare now the region's single largest employment sector.

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OSF HealthCare's downtown Peoria headquarters

OSF HealthCare is headquartered in downtown Peoria and has been named one of the nation's best employers by Forbes -- a real, substantial regional healthcare anchor directly within the city.

UnityPoint Health and a growing regional sector

UnityPoint Health runs a substantial parallel regional system alongside OSF, with healthcare overall accounting for roughly 18% of regional jobs -- larger than manufacturing's roughly 13% share.

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Key takeaways

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Last reviewed: 2026-08-25. Independent research; not financial, tax, or legal advice -- confirm current figures with a local professional before making a decision.